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These may include: Pressure necrosis (tissue death) from the tubing Injury to the skin around the wound Growth of granulation tissue into the foam dressing Increased pain initially, due to reduced pressure as the foam collapses Contact dermatitis due to the adhesive transparent tape Fistula (tunnel) formation Development of skin cancer as a result of increased blood flow in the wound bed (very rare)

Because of the amount of damaged tissue, there are many endotoxins being released into the wound, which can impair the activity of the fibroblasts and keratinocytes

Celine Dion circa 1987 The singer went all out in a denim-on-denim look while in Montreal